Many TPIPE options are long, with many parameters, and are hard to remember. I am not recommending environment variables to do the job, but some way to create and use a "library" of TPIPE aliases would keep me from having to go to the help. Here's an example.
I had to go to the help to remember the "4,1,0,0,0,0,0,0,0,". Here's an alternative (again, I'm not recommending envvars).
Ideal (???) might be some way to define "rep" so that I could later say
v:\> echo 222 | tpipe /replace=4,1,0,0,0,0,0,0,0,"\x32","\x33" 333
v:\> set rep=/replace=4,1,0,0,0,0,0,0,0, v:\> echo 222 | tpipe %[rep]"\x32","\x33" 333
echo 222 | tpipe /rep="\x32","\x33"